In situ TEM Liquid Platform with Heating or Biasing

In Situ TEM Liquid, Liquid Biasing and Liquid Heating; perform precisely controlled dynamic liquid state experiments in your TEM.

  • Denssolutions strean in situ team platform

    Key Features

    • Fast switching Precision channel with no dead volume, which enables zero-contamination switching of the sample environment in seconds
    • Accurate Liquid flow and pressure A pressure-based liquid pump allows precision independent control of liquid low and gas pressure
    • Improved Imaging The liquid thickness can be controlled for optimal image resolution and contrast
    • Extended Chemistry Different gases can be used to pressurise liquids to create reactive saturated solutions
    • Modular Design Facilitates exchange of critical components to eliminate any cross-contamination

Modular Sample Holder

DENSoslutions modular tip design for TEM platforms

Ensure a clean experiment with a removable tip & tubing

Once the Nano-Cell is placed into self-aligning precision slot within the Sample Holder tip, the O-rings and lid are sealed and the system is ready for vacuum testing. As the tip is removable, the internal liquid tubing can be replaced at any time to avoid clogging/cross-contamination and can be cleaned

The New Nano-Cell

Controlled liquid environment within the microscope

DENSsolutions nano-cell for in situ TEM platforms

The Stream Nano-Cells radically change the way experiments in liquid are performed.


  • Defined liquid channel and no dead volumes
  • Pressurized inlet and outlet to accurately define pressure and flow rate, independently
  • Drastically reduced bulging for easier imaging

The Nano-Cell consists of a top (A) and bottom chip (B), which together form a sealed compartment that enable you to safely perform liquid experiments inside the TEM.

The top and bottom chip both contain electron transparent windows (C&D) which enable you to image your sample. The sample is located on the bottom window (D) and can be exposed to heating or biasing, depending on the type of bottom chip you use.   

Liquid Supply System – LSS

DENSsolutions Liquid supply system for precise cointrol of the microfluidic environment for LPEM

The Liquid Supply Systems (LSS) which affords users unique capabilities with precise fluidic control for in situ TEM experiments and addresses the biggest issue with in situ liquid phase TEM.

Using the new LSS, researchers will have full control over the microfluidic environment inside the Nano-Cell, i.e. the environmental MEMS sample carrier of the Stream, while simultaneously being able to independently control biasing or heating of their sample. This new system can be fully integrated providing greater flexibility and ease-of-use and while at the same time enabling complex imaging experiments in fewer steps.

Read more

  • In Situ TEM Study of a Battery Using the STREAM Liquid Platform

    The behaviour of a battery cell was dynamically observed in a TEM using a DENSsolutions STREAM in situ TEM liquid platform. The structure of the battery electrode can be seen to change under different/precisely controlled flow rates and biasing.

  • All
  • Biological Microscopy
  • CL
  • CLEM
  • Computed Tomography
  • Diffraction Imaging
  • EBSD
  • EDS
  • Electron Beam Lithography (EBL)
  • Electron Microscopy
  • Fabrication
  • FIB
  • In situ
  • Micro XRF
  • Microscopy
  • Protein
  • Protein Crystallography
  • SEM
  • TEM
  • Thermal Probe Lithography
  • WDS
  • X-ray Imaging
  • X-ray Microscopy