Fluicell BioPen Systems

Microfluidic systems for targeting single cells

Precise control of the cellular micro environment via microfluidics

  • Key Features

    • Target single cells Target just one or a small number of adherent cells to particular compounds
    • Rapid delivery Deliver four different compounds to just a single cell or part of a cell with sub-second exchange time.
    • Low compound consumption The four integrated wells containing less than 35 μl, overcome typical dead volume problem of external tubing, reducing significantly the use of expensive reagents.
    • Combination with other probing devices The pipette tip has been optimized to fit into practically any micromanipulation environment allowing combination with other probes such as patch-clamp pipettes, optical fibers or electrodes.
    • No glass or tip breakage The pipette tips are made from a flexible biocompatible material so that unlike glass pipettes they won’t break upon contact with the hard surface.
    • No contamination The pipette tip has been developed from an hydrodynamically confined flow principle, enabling contamination-free confinement of one miscible liquid inside another.

Control the microenvironment of your cells by targeting one cell at the time.

The ability to target one or a small number of cells requires precision control over the environment immediately surrounding a cell.

BioPen PRIME and BioPen FLEX systems are easy-to-use microfluidic devices for maintaining a local delivery of molecules to single-cells, enabling control of the chemical environment around single intact cells in tissue or cell cultures.

  • See the BioPen in action. Collect unprecedented data quality at high resolution by controlling how much, when and where your compounds meet your cells.