Intravital Microscopes – Confocal, 2-Photon & Smart

Intravital microscopy is a powerful preclinical imaging tool that enables real-time visualisation of biological processes within living organisms. It allows researchers to observe dynamic events in real-time in their native physiological environment. It can provide valuable insights into cellular behavior, interactions and responses within living systems over extended time periods.

The technique has application in many areas of biomedical research including, but not limited to immunology, neuroscience, drug development and cancer research

Intravital Microscopy Series 3

The latest iteration of IVIM Technology’s IVM series microscopes feature and all-in-one design that can incorporate confocal microscopy, 2-photon microscopy and smart features, or any combination thereof. This platform provides researchers with a cutting-edge system for cellular exploration that will help improve the success rates of new drug candidates by providing better insights into how they perform and interact with tissues at the cellular level.

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Model	FS	CMS3	MS3	CM3	M3	C3
Confocal	✔	✔	✔	✔		✔
2-Photon	✔	✔		✔	✔
Smart	✔	✔	✔
Overview	The IVM-FS system offers the same functions as the IVM-CMS3 system, but caters for animals larger than mice and rats (older than 6 weeks). The dark curtain provided eliminates the need for a dedicated dark room or specific space just for the microscope.	CMS3 stands out as the world’s most compact and affordable dual-mode intravital confocal and two-photon microscope, offering versatile functionality in a single, streamlined box. Leveraging the confocal laser units from IVM-C3 and the compact two-photon laser unit from IVM-MS3, IVM-CMS3 features a one-switch (one-click) mode changing capability, providing convenient multi-purpose use for intravital functional imaging while optimizing space and minimizing costs. Explore the efficient and cost-saving capabilities of IVM-CMS3 for your diverse imaging needs.	It represents thesmart evolution of IVM-M3, an All-in-One Two-Photon Intravital Microscopy system meticulously optimized for in vivo imaging. This system seamlessly integrates a compact, high-stability, and maintenance-free fs-pulse laser unit into a single box. With the ability to focus on deep tissues at a fixed wavelength of 920nm, IVM- MS3 serves as an exceptional resource for researchers with specific targets, offering optimal functionality within limited resources and budget constraints. Explore the possibilities with IVM-MS3 for efficient and budget-friendly in vivo imaging.	It delivers exceptional contrast and resolution with its tunable Two-Photon laser unit.It allows focus on samples at desired wavelengths ranging from as low as 690 nm to as high as 1050 nm, and everything in between. This cutting-edge system seamlessly combines the strengths of both Confocal and Two-Photon microscopy, offering limitless possibilities for three- dimensional imaging of living cells whether near the skin or deep within tumors in small animals. Explore the potential of IVM-CM3 for advanced and versatile imaging in your research.	A seamlessly combines the flexibility of a traditional converted microscope with the high-resolution imaging capabilities of second-harmonic generation microscopy. Featuring a fully automated tunable fs-pulse NIR laser system, IVM-M3 excels in deep tissue imaging by using less-scattering NIR wavelengths. The comprehensive control functionality of the fs- laser system is integrated with the two-photon imaging software, ensuring user convenience with various automation algorithms. Experience advanced imaging with IVM-M3 for your research needs.	A highly integrated system for in vivo imaging, offering significantly enhanced detection efficiency, optical resolution, and image contrast compared to conventional fluorescence microscopy. With a 4-wavelength laser and four high-sensitivity confocal detectors, IVM-C3 enables multi-dimensional views of living cells and tissues in 3D or 4D, while supporting up to four different colors.

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Applications

IVIM Technology’s intravital microscopes have been deployed to a wide variety of living tissues and scenarios. Some of these are summarised below.