Extracellular Vesicles

Extracellular vesicles (EVs) play key roles in cell-to-cell communication. EVs can cross biological barriers (such as the blood-brain barrier) and get internalized into the cell with a high degree of specificity.

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Biosafety Cabinets

Until recently, due to their size and design, the majority of super-resolution microscopes have not been able to support research in enclosed, ventilated biosafety cabinets. But things are changing.

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Viral Particle Imaging

Viral particles vary greatly in size, but are typically below the resolution limit of conventional light microscopy. Recently, super-resolution techniques have been employed to study their mechanistic and functional characteristics at a single-molecule level.

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Tracking Single Molecules and Vesicles in cells

The Nanoimager can track single molecules and vesicles in both bacterial and eukaryotic cells with super-resolution microscopy.

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Tracking Viral Particles

Understanding and quantifying viral particle behavior.

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Quantitative Cellular Imaging

Gain detailed understanding of cellular features through multi-color super-resolution microscopy with advanced data analysis including colocalization and clustering.

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Protein Complex Assembly

Intensity measurements, super-resolution and multi-color labeling for characterizing protein complexes and their assembly.

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DNA Conformational Changes

A dynamic, real-time nanoscale ruler, now a general tool for characterizing molecular interactions and structure with Alternating Laser Excitation (ALEX) support.

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DNA-PAINT shows sub-20nm resolution

DNA-PAINT provides easy localization-based super-resolution with nanorulers from GATTAquant GmbH.

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Exosomes and Microvesicles

Understanding the structure and function of extracellular vesicles through super-resolution microscopy.

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